Research Field
Autoimmune encephalitis
Brief Summary
Dr. Soon-Tae Lee serves as a Professor of Neurology at Seoul National University Hospital, with a primary focus on autoimmune neurology. His dedication lies in developing novel treatments for autoimmune encephalitis (AE) and leading clinical and translational studies utilizing innovative immunotherapeutic agents tailored for this condition. He also operates the sole antibody diagnostic lab for autoimmune encephalitis in Korea. Despite the rapid advancements in AE treatments, many patients still exhibit poor responses to current immunotherapies, resulting in significant long-term disease burdens. To address this, his research focuses on understanding the mechanisms behind treatment refractoriness and conducting clinical trials with novel immunotherapeutic agents. He has published over 350 SCI papers, with an h-index of 70. His key contributions include the following:
• The development and validation of the Clinical Assessment Scale in Autoimmune Encephalitis (CASE score)
• The implementation of tocilizumab in AE/NORSE treatment protocols
• The characterization of seronegative AE, MOG antibody-associated encephalitis (MOGAE), and cryptogenic NORSE
• The discovery of HLA-association in LGI1 encephalitis
• The clinical trials in AE and related disorders.
Education
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2005-2010
서울대학교 의과대학 뇌신경과학 박사
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2003-2005
서울대학교 의과대학 뇌신경과학 석사
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1995-2001
서울대학교 의과대학 의학과 학사
Career
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2020-현재
서울대학교병원 신경과 교수
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2021-2022
Visiting Scholar, Center for Encephalitis and Meningitis, UCSF
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2016-2020
서울대학교병원 신경과 부교수
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2012-2016
서울대학교병원 신경과 조교수
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2011-2012
임상연수 및 박사후연구원 (DFCI/BWH, Harvard University)
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2009-2011
서울대학교병원 신경과 전임의
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2002-2006
서울대학교병원 신경과 전공의