Introduction

The Medium & Large Animal Facility is a husbandry facility for medium and large laboratory animals, comprising cats (1 room), dogs (2 rooms), pigs (1 room), goats (2 rooms), an inspection & quarantine room (1 room), and a recovery room (1 room). It houses Conventional-grade medium and large animals and is equipped with a variety of experimental spaces required for preclinical studies, including surgery rooms, an ICU, and an anatomy & physiology laboratory. A clean environment is maintained through regular environmental and microbiological monitoring, and a range of experimental technical support services is provided.

A constant temperature and humidity system maintains a stable environment year-round according to the standards below.

Facility Composition

  • Dog: Rooms 9107, 9108, 9209
  • Pig: Room 9109
  • Goat / Sheep: Rooms 9110, 9208
  • Cat: Room 9111
  • Inspection & Quarantine Room: Room 9210
  • Recovery Room: Room 9210

Housed Animal Species

  • Dog (Beagle, etc.)
  • Pig (including minipig)
  • Goat / Sheep
  • Cat

Husbandry Environment Standards

Husbandry environment standards of the Medium & Large Animal Facility
ItemAnimal RoomOther Areas
Temperature (°C)18 ~ 29-
Humidity (%)30 ~ 7030 ~ 70
Illuminance (Lux)800 ~ 1,100300 ~ 600
Noise (dB)60 or below60 or below
Ammonia (ppm)20 or below-
Settle Plate Count (CFU/plate)1003
Differential PressureExterior → Corridor: 2 or above / Corridor → Animal Room: 1 ~ 3
  • Light/Dark Cycle: 12 hours light / 12 hours dark (automatic control)
  • Ventilation Rate: 10 ~ 15 air changes per hour

Laboratory & Surgery Room Environment Standards

Environment standards for the laboratory, surgery room, and primate surgery room
ItemLaboratorySurgery RoomPrimate Surgery Room
Temperature (°C)18 ~ 2918 ~ 2918 ~ 29
Humidity (%)30 ~ 7030 ~ 7030 ~ 70
Illuminance (Lux)300 ~ 600800 ~ 1,100800 ~ 1,100
Noise (dB)60 or below60 or below60 or below
Ammonia---
Settle Plate Count (CFU/plate)333
Differential Pressure-1 or above0.8 ~ 1.6

Equipment

Below is a list of major equipment available in the surgery rooms, ICU, and anatomy & physiology laboratory within the Medium & Large Animal Facility. Each item is managed at all times by the person in charge and may be used by advance reservation.

Medium & Large Animal Facility equipment — room name, equipment name, quantity
Room NameEquipment NameQty
Surgery Room 1Anesthesia machine1
Defibrillator1
Electrosurgical generator (bipolar)1
Electrosurgical generator (monopolar)1
Hyper-hypo thermia1
Infusion pump1
Operating light2
Laparoscope2
Laparoscope monitor2
Patient monitor1
Patient monitor-monitor1
Surgery table1
Water bath1
Surgery Room 2Anesthesia machine1
Electrosurgical generator (monopolar)1
ECG1
Operating light1
Hyper-hypo thermia1
Patient monitor1
Surgery table1
Surgery Room 3Anesthesia machine2
Defibrillator1
Electrosurgical generator (bipolar)1
Electrosurgical generator (monopolar)1
Heart lung machine1
Hemotherm (cooler-heater)1
Hyper-hypo thermia1
Operating light2
Patient monitor1
Patient monitor-monitor2
Surgery table2
View box1
Water bath1
Room 9202 (Scrub Room)Scrub station1
Syringe pump (9 units)1
ICUOperating light1
Patient monitor3
Patient monitor-monitor3
Electrosurgical generator (monopolar)3
Anesthesia machine1
Microscope (operating)2
View box1
Anatomy & Physiology LaboratorySurgery table1
Rodent Anesthesia System1
Microscope1
Medical Motor drive Photography system1
Clean Bench1
Autoclave1
Fume adsorber / Slide warmer / Copy stand1 each

※ Advance inquiry and reservation with the person in charge are required before using equipment.

Technical Support

Technical Support Operating Principles

  • Support is provided to the extent that it does not interfere with the core duties of the Preclinical Laboratory.
  • Technical support that directly affects experimental results is, in principle, not provided; however, where unavoidable grounds are recognized, it may be provided on an exceptional basis at the discretion of the Preclinical Laboratory.
  • Research teams receiving technical support must pay the fee for each item.

Technical Support Items

Medium & Large Animal Facility technical support items
CategoryMethodAnimal Species
Blood SamplingVenous (ear, leg)Dog, pig, goat, sheep
Whole bloodDog, goat
AdministrationOralDog, pig, goat, sheep
Intraperitoneal
Subcutaneous
Intramuscular
Intravenous
Euthanasia-Dog, pig, goat
Necropsy-Dog, pig, goat

※ If support beyond the items listed above is needed, please inquire with the person in charge in advance.

Contact

  • Person in charge: Kim Sa-hoon
  • Phone: 02-2072-1901
  • Email: (to be added)